Pure Encapsulations' MSM (methylsulfonylmethane or dimethylsulfone) is a source of organic sulfur found naturally in the human body. MSM, the major metabolite of DMSO (dimethyl sulfoxide), is 34% elemental sulfur, a compound which is crucial in maintaining healthy tissues. While sulfur supports many funcÂtions, it is well known for maintaining connective tissue health. Sulfur also supports tissue containing significant amounts of collagen and keratin, including hair, skin, and nails. Sulfur is essential in methionine, cysteine and serum protein metabolism. Preliminary evidence suggests that MSM may also provide potential support for healthy immune and respiratory function.